Post-stroke cognitive trajectories:
The Oxford Cognitive Screening Programme
The recovery of cognitive problems after stroke is still poorly understood, but preliminary data from our cognitive screening programme suggests that there are differences for contrasting cognitive domains.
The aim of this research is to evaluate how cognitive measures taken at an acute stage evolve over time post stroke, from acute to 6 months, as well as into long-term chronic stages post stroke. New research in our group aims to determine individualised prediction modeling, to predict recovery, based on acute cognitive data. In the longer term, having a better understanding of the natural time course of cognitive recovery, and its link to functional outcomes, is essential in being able to assess any added contributions when interventions are introduced to improve performance.
Publications
- Milosevich E, Kusec A, Pendlebury ST, Demeyere N. Domain-specific cognitive impairments, mood and quality of life 6 months after stroke. Disability and Rehabilitation. 2025 Jan 16;47(2):435–44.
- Demeyere N & Moore MJ (2024). Innovations and challenges in predicting cognitive trajectories after stroke. Brain Communications. 2024 Oct 16;fcae364.
- Overman MJ, Binns E, Milosevich ET, Demeyere N.(2024) Recovery of Visuospatial Neglect With Standard Treatment: A Systematic Review and Meta-Analysis. Stroke.
- Kusec A, Milosevich E, Williams OA, Chiu EG, Watson P, Carrick C, … & Demeyere N. (2023) Long-term psychological outcomes following stroke: the OX-CHRONIC study. BMC Neurology. 30;23(1):426.
- Milosevich E, Moore MJ, Pendlebury S, & Demeyere N. (2023) Domain-specific cognitive impairment 6 months after stroke: the value of early cognitive screening. International Journal of Stroke. 2023 Sep 25.
- Moore MJ, Vancleef, K., Riddoch, J. M., Gillebert, C. R., & Demeyere, N. (2021). Recovery of Visuospatial Neglect Subtypes and Relationship to Functional Outcome Six Months After Stroke. Neurorehabilitation and neural repair, 35(9), 823–835.
- Mole, J. A., & Demeyere, N. (2020). The relationship between early post-stroke cognition and longer term activities and participation: a systematic review. Neuropsychological rehabilitation, 30(2), 346–370.
- Demeyere, N., Sun, S., Milosevich, E., & Vancleef, K. (2019). Post-stroke cognition with the Oxford Cognitive Screen vs Montreal Cognitive Assessment: a multi-site randomized controlled study (OCS-CARE). AMRC Open Research, 1, 12.
- Demeyere, N., & Céline R, G.. (2019). Ego- and allocentric visuospatial neglect: dissociations, prevalence, and laterality in acute stroke. Neuropsychology, 33(3), 490–498.
- Moore, M. J., Vancleef, K., Shalev, N., Husain, M., & Demeyere, N. (2019). When neglect is neglected: nihss observational measure lacks sensitivity in identifying post-stroke unilateral neglect. J neurol neurosurg psychiatry, jnnp–2018
Funding
OX-CHRONIC – Long term psychological consequences of stroke. Stroke Association Priority Programme Grant (2019-2023)
Visuo-spatial neglect subtypes: impact and recovery. Doctoral Stroke Association Fellowship (Margaret Moore, 2018-2021)
Predicting daily life functioning from visual perception screening. Postdoctoral Stroke Association Fellowship (Kathleen Vancleef, 2017-2020)
Aligning formal and functional assessments of cognition post stroke. Stroke Association Lectureship (2015-2020)
OCS-CARE. Stroke Association award (PI Glyn Humphreys)