- Visuospatial Neglect
Visual neglect is a common condition which occurs following brain damage produced by strokes. Visual neglect causes stroke survivors to become unable to perceive objects, events, and people located in one side of space. Patients with this condition fail to notice loved ones approaching, struggle to read their favourite books, and are often unable to find important items when preparing food or drink. Past research has suggested that there is more than one kind of visual neglect, but little is known about how these separate conditions cause different problems in the way stroke survivors interact with the world. Visual neglect can be easily detected using simple tests, but it is not yet clear how the neglect severity scores assigned by these tests are related to the actual real-world impairment stroke survivors encounter while they are recovering. Additionally, it is not yet clear whether patients who experience different kinds of visual neglect are more or less likely to fully recover from their stroke.
The purpose of this research is to address these issues by tracking recovery progress in stroke survivors. We have tracked how stroke survivors with visual neglect recover over time, investigated how clinical tests for neglect can help predict how impaired specific patients will be in daily life, and to determine whether the presence of visual neglect following stroke can help predict how well individual patients will recover over time. We have also done extensive research into the neural bases of different types of neglect.
This study was funded by a Stroke Association Postgraduate Fellowship to Dr Moore, with ongoing further research under the broader OCS-Recovery study (REC reference 18/SC/0550), supported by the UK Clinical Research Network.
Moore, M. J., Milosevich, E., Mattingley, J. B., & Demeyere, N.. (2023). The neuroanatomy of visuospatial neglect: A systematic review and analysis of lesion-mapping methodology. Neuropsychologia, 108470.
Moore, M., Milosevich, E., Beisteiner, R., Bowen, A., Checketts, M., Demeyere, N., Fordell, H., Godefroy, O., Laczó, J., Rich, T., Williams, L., Woodward-Nutt, K., & Husain, M.. (2022). Rapid screening for neglect following stroke: A systematic search and European Academy of Neurology recommendations. European journal of neurology.
Moore, M. J., Vancleef, K., Riddoch, J. M., Gillebert, C. R., & Demeyere, N.. (2021). Recovery of Visuospatial Neglect Subtypes and Relationship to Functional Outcome Six Months After Stroke. Neurorehabilitation and neural repair, 35(9), 823–835.
Moore, M. J., Driscoll, R., Colwell, M., Hewitt, O., & Demeyere, N.. (2021). Aligning formal and functional assessments of Visuospatial Neglect: A mixed-methods study. Neuropsychological rehabilitation, 1–20.
Moore, M. J., Shalev, N., Gillebert, C. R., & Demeyere, N.. (2020). Dissociations within neglect-related reading impairments: egocentric and allocentric neglect dyslexia. Journal of clinical and experimental neuropsychology, 42(4), 352–362.
Huygelier, H., Moore, M. J., Demeyere, N., & Gillebert, C. R.. (2020). Non-spatial impairments affect false-positive neglect diagnosis based on cancellation tasks. Journal of the international neuropsychological society.
Lay report here
Moore, M. J., Vancleef, K., Shalev, N., Husain, M., & Demeyere, N. (2019). When neglect is neglected: nihss observational measure lacks sensitivity in identifying post-stroke unilateral neglect. J neurol neurosurg psychiatry, jnnp–2018.
Lay report here
- Lay report here