Spatial and Executive (in)Attention

Fundamental Cognitive Neuropsychology: Attention

In terms of theoretical cognitive neuropsychology, our group has a longstanding tradition and interest in (in)attention, ranging in topics from spatial-based, to feature-based and temporally evolving attention. In particular, post-stroke visuo-spatial neglect is a continuing key topic of interest within the group:

Visuospatial Neglect

The purpose of this research is to address these issues by tracking recovery progress in stroke survivors. We have tracked how stroke survivors with visual neglect recover over time, investigated how clinical tests for neglect can help predict how impaired specific patients will be in daily life, and to determine whether the presence of visual neglect following stroke can help predict how well individual patients will recover over time. We have also done extensive research into the neural bases of different types of neglect.

Publications

Publications

• Overman MJ, Binns E, Milosevich ET, Demeyere N.(2024) Recovery of Visuospatial Neglect With Standard Treatment: A Systematic Review and Meta-Analysis. Stroke.
• Gurd J, Demeyere N, & Moore MJ. (2023). Attentional and lexical factors underlying word-centred neglect dyslexia errors in healthy readers. Attention, perception, & psychophysics.
• Moore MJ, Milosevich E, Mattingley JB, & Demeyere N. (2023). The neuroanatomy of visuospatial neglect: A systematic review and analysis of lesion-mapping methodology. Neuropsychologia, 108470.
• Moore MJ, Demeyere N. (2023) Word-centred neglect dyslexia as an inhibitional deficit: A single case study. Neuropsychologia. 2023 Mar 9;108502.
• Moore M. J., Milosevich E., Mattingley J. B., & Demeyere N. (2023). The neuroanatomy of visuospatial neglect: A systematic review and analysis of lesion-mapping methodology. Neuropsychologia, 108470.
• Moore M. J., & Demeyere N. (2022). Multiverse to inform neurological research: an example using recovery outcome of neglect. Journal of neurology, 269(1), 233–242.
• Moore M., Milosevich E., Beisteiner R., Bowen A., Checketts M., Demeyere N., Fordell, H., Godefroy, O., Laczó, J., Rich, T., Williams, L., Woodward-Nutt, K., & Husain, M.. (2022). Rapid screening for neglect following stroke: A systematic search and European Academy of Neurology recommendations. European journal of neurology.
• Moore, M. J., Vancleef, K., Riddoch, J. M., Gillebert, C. R., & Demeyere N. (2021). Recovery of Visuospatial Neglect Subtypes and Relationship to Functional Outcome Six Months After Stroke. Neurorehabilitation and neural repair, 35(9), 823–835.
• Moore, M. J., Driscoll, R., Colwell, M., Hewitt, O., & Demeyere N. (2021). Aligning formal and functional assessments of Visuospatial Neglect: A mixed-methods study. Neuropsychological rehabilitation, 1–20.
• Moore, M. J., Gillebert, C. R., & Demeyere, N. (2021). Right and left neglect are not anatomically homologous: A voxel-lesion symptom mapping study. Neuropsychologia, 162, 108024.
• Moore, M. J., & Demeyere, N. (2020). Dissociating spatial attention from neglect dyslexia: A single case study. Cortex, 130, 246–256.
• Moore, M. J., Shalev, N., Gillebert, C. R., & Demeyere, N. (2020). Dissociations within neglect-related reading impairments: egocentric and allocentric neglect dyslexia. Journal of clinical and experimental neuropsychology, 42(4), 352–362.
• Huygelier, H., Moore, M. J., Demeyere, N., & Gillebert, C. R. (2020). Non-spatial impairments affect false-positive neglect diagnosis based on cancellation tasks. Journal of the international neuropsychological society.
• Moore, M. J., & Demeyere, N. (2018). Neglect dyslexia as a word-centred impairment: a single case study. Cortex.
• Moore, M. J., Vancleef, K., Shalev, N., Husain, M., & Demeyere, N. (2019). When neglect is neglected: nihss observational measure lacks sensitivity in identifying post-stroke unilateral neglect. J neurol neurosurg psychiatry, jnnp–2018.
• Moore, M. J., & Demeyere, N. (2017). Neglect dyslexia in relation to unilateral visuospatial neglect: a review. Aims neuroscience, 4(4).
• Demeyere, N., & Gillebert CR. (2019). Ego- and allocentric visuospatial neglect: dissociations, prevalence, and laterality in acute stroke. Neuropsychology, 33(3), 490–498.

Funding

Visuo-spatial neglect subtypes: impact and recovery. Doctoral Stroke Association Fellowship (Margaret Moore, 2018-2021)

Executive & Sustained Attention 

Publications

• Hobden G, Moore MJ, Mair G, Pendlebury ST, & Demeyere N (2024). Poststroke Executive Function in Relation to White Matter Damage on Clinically Acquired CT Brain Imaging. Cognitive and Behavioral Neurology. 2024 Mar;37(1):23.
• Moore MJ, Hearne L, Demeyere N, Mattingley JB (2023). Comprehensive voxel-wise, tract-based, and network lesion mapping reveals unique architectures of right and left visuospatial neglect. Brain Structure & Function.
• Brosnan, MB, Dockree, PM, Harty, S, Pearce, DJ., Levenstein, J. M., Gillebert, C. R., Bellgrove, M. A., O’Connell, R. G., Robertson, I. H., & Demeyere, N. (2022). Lost in Time: Temporal Monitoring Elicits Clinical Decrements in Sustained Attention Post-Stroke. Journal of the international neuropsychological society, 28(3), 249–257.
• Rowe, K., Duta, M., Demeyere, N., Wagner, R. G., Pettifor, A., Kahn, K., Tollman, S., Scerif, G., & Stein, A. (2021). The relationship between executive function, risky behaviour and HIV in young women from the HPTN 068 study in rural South Africa. Aids care, 33.
• Huygelier, H., Moore, M. J., Demeyere, N., & Gillebert, C. R. (2020). Non-spatial impairments affect false-positive neglect diagnosis based on cancellation tasks. Journal of the international neuropsychological society.
• Shalev, N., Humphreys, G., & Demeyere, N. (2018). Manipulating perceptual parameters in a continuous performance task. Behavior Research Methods, 50(1), 380–391.
• Shalev, N., De Wandel, L., Dockree, P., Demeyere, N., & Chechlacz, M. (2018). Beyond time and space: the effect of a lateralized sustained attention task and brain stimulation on spatial and selective attention. Cortex, 107, 131–147.
• Varjačić, A., Mantini, D., Levenstein, J., Slavkova, E. D., *Demeyere, N., & *Gillebert, C. R. (2018). The role of left insula in executive set-switching: lesion evidence from an acute stroke cohort. Cortex, 107, 92–101.
• Varjacic, A., Mantini, D., Demeyere, N., & Gillebert, C. R. (2018). Neural signatures of trail making test performance: evidence from lesion-mapping and neuroimaging studies. Neuropsychologia, 115, 78–87.
• Rosenberg, M., Pettifor, A., Duta, M., Demeyere, N., Wagner, R. G., Selin, A., MacPhail, C., Laeyendecker, O., Hughes, J. P., Stein, A., & others. (2018). Executive function associated with sexual risk in young south african women: findings from the hptn 068 cohort. Plos One, 13(4), e0195217.
• Finsterwalder, S., Demeyere, N., & Gillebert, C. R. (2017). Deficit in feature-based attention following a left thalamic lesion. Neuropsychologia, 102, 1–10.
• Shalev, N., Humphreys, G., & Demeyere, N. (2016). Assessing the temporal aspects of attention and its correlates in aging and chronic stroke patients. Neuropsychologia, 92, 59–68.
• Antoniades, C. A., Demeyere, N., Kennard, C., Humphreys, G. W., & Hu, M. T. (2015). Antisaccades and executive dysfunction in early drug-naive parkinson’s disease: the discovery study. Movement disorders, 30(6), 843–847.
• Chechlacz, M., Terry, A., Demeyere, N., Douis, H., Bickerton, W., Rotshtein, P., & Humphreys, G. W. (2013). Common and distinct neural mechanisms of visual and tactile extinction: a large scale vbm study in sub-acute stroke. Neuroimage: clinical, 2, 291–302.
• Demeyere, N., Rzeskiewicz, A., Humphreys, K. A., & Humphreys, G. W. (2008). Automatic statistical processing of visual properties in simultanagnosia. Neuropsychologia, 46(11), 2861–2864.

Funding

EU Marie Curie Initial Training Network. Individualised Diagnostics & Rehabilitation of Attention Disorders. (PI Humphreys)